On 8-10 June 2021, world leaders will convene at the United Nations High Level Meeting on HIV and AIDS. Within the framework of the new UNAIDS Global AIDS Strategy for 2021-2026, the High-Level Meeting will yield a political declaration that aims to end AIDS by ending inequalities. Against this backdrop, UNAIDS, UNICEF, WHO and partners call on world leaders to make the necessary commitments and investments to get back on track towards ending AIDS in children and adolescents by 2030.