ART and Treatment

Improving HIV Service Delivery for Infants, Children and Adolescents: Towards a framework for collective action

admin — Tue, 28 Jan 2020 19:15:11 +0000

Improving HIV Service Delivery for Infants, Children and Adolescents: Towards a framework for collective action admin Tue, 01/28/2020 - 21:15

In June 2019, UNICEF convened a group of about 40 global experts from 24 organizations and institutions to advance the collective thinking on paediatric HIV service delivery. The aim of this “think tank” consultation was to build consensus on the specific programme interventions that need to be scaled up to improve the quality of HIV treatment services and reach more infants, children and adolescents with these lifesaving medicines.

Participating organizations included:

Aidsfonds
Africaid-Zvandiri
African Network for the Care of Children Affected by HIV/AIDS
(ANECCA)
Baylor College of Medicine
Centers for Disease Control and Prevention (CDC)
Clinton Health Access Initiative (CHAI)
Elizabeth Glaser Pediatric AIDS Foundation (EGPAF)
ELMA Philanthropies
Health Innovations Kenya
FHI 360
ICAP at Columbia University
Joint United Nations Programme on HIV/AIDS (UNAIDS)

Kenya Ministry of Health
Office of the Global AIDS Coordinator (OGAC)
Pact
Pediatric-Adolescent Treatment Africa (PATA)
Positive Action for Children Fund (PACF) / ViiV Healthcare
Réseau Enfants et VIH en Afrique (EVA)
United Nations Children’s Fund (UNICEF)
University of Nairobi
United States Agency for International Development (USAID)
World Health Organization (WHO)
World Council of Churches – Ecumenical Advocacy Alliance (WCC–EAA)
Yale University

Experts addressed the gaps in the continuum of care which are causing children to be missed before they are tested, before they are given their test results and before they are provided with lifelong treatment and care. Read more about the evidence base and the call for action in the brief above.

Paediatric and Adolescent Treatment

Organization Tag

Region Tags

Population Tags

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Health systems strengthening

Maternal, newborn and children health

Policy/Enabling Environment

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Brief

Strategy

Year Tags

2019

Download file(s)

Brief: Improving HIV Service Delivery for Infants Children and Adolescents

Paediatric Service Delivery Framework

cmannikarottu — Tue, 26 Nov 2019 16:54:16 +0000

Paediatric Service Delivery Framework cmannikarottu Tue, 11/26/2019 - 18:54

The paediatric service delivery framework presents strategies to address bottlenecks across the continuum of care for each population: infants, children and adolescents. This includes keeping mothers who receive interventions for the prevention of mother-to-child HIV transmission (PMTCT) and their infants in care; locating missing infants, children and adolescents through family and index testing; linking those diagnosed with HIV to services; treating them with efficacious regimens and retaining them on treatment to achieve viral suppression. It describes comprehensive and targeted service delivery models, which emphasize strong linkages between testing, treatment and care, and between communities and facilities.

The framework was developed by a group of global experts who were convened by UNICEF in June 2019 to advance the collective thinking on paediatric HIV service delivery. The partnership's analysis of current evidence and specific programme interventions that need to be scaled up to improve the quality of HIV treatment services and reach more infants, children and adolescents with these lifesaving medicines is presented here.

The full framework, policy briefs and supporting worksheets are available for download (updated July 2020).

Paediatric and Adolescent Treatment

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Region Tags

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Family centred care/services

Document Type Tags

Brief

Strategy

Year Tags

2019

Download file(s)

Framework: Improving HIV Service Delivery for Infants, Children and Adolescents (WEB)

Framework: Improving HIV Service Delivery for Infants, Children and Adolescents (PRINT)

Worksheet: Assessing the situation

Paediatric Abacavir/Lamivudine/Dolutegravir (pALD) fixed-dose combination: Introduction and rollout planning considerations for national programmes

rlekirkegaard — Thu, 21 Dec 2023 17:30:23 +0000

Paediatric Abacavir/Lamivudine/Dolutegravir (pALD) fixed-dose combination: Introduction and rollout planning considerations for national programmes rlekirkegaard Thu, 12/21/2023 - 19:30

Dolutegravir (DTG)-based HIV treatment regimens are recommended by the World Health Organization for children living with HIV (CLHIV) who weigh at least 3 kg. In 2020, the United States Food and Drug Administration (US FDA) granted tentative approval of paediatric DTG 10 mg scored, dispersible tablets (pDTG) for CLHIV weighing a minimum of 3 kg and at least four weeks of age. In early 2021, national HIV programmes in low- and middle-income countries (LMICs) began to transition CLHIV from treatment regimens containing non-nucleoside reverse transcriptase inhibitor (NNRTI) and lopinavir/ritonavir to pDTG. As of the last quarter of 2022, at least 73 countries have already placed or received orders for pDTG1 and an estimated 130,000 children have transitioned to pDTG. pDTG currently is administered along with optimised backbone antiretrovirals (ARVs) such as abacavir/lamivudine 120/60 mg scored dispersible tablets (pABC/3TC) per the WHO’s 2021 Consolidated HIV Guidelines.

This brief aims to inform the transition from pDTG + pABC/3TC to the new fixed-dose combination (FDC) dispersible tablet of paediatric ABC/3TC/DTG 60/30/5 mg (pALD).

Paediatric and Adolescent Treatment

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Topic Tags

Paediatric ARVs and formulations

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Brief

Year Tags

2023

Download file(s)

pALD introduction and rollout planning

Getting back on track to ending AIDS in Children

rlekirkegaard — Thu, 16 Nov 2023 12:45:57 +0000

Getting back on track to ending AIDS in Children rlekirkegaard Thu, 11/16/2023 - 14:45

In this viewpoint Getting back on track to ending AIDS in Children: It could just be easier than you think, published in the Journal of the International AIDS Society on World Children's Day, 20 November 2023, UNICEF reviews the global inequities faced by children and adolescents living with HIV and highlights three strategies to end AIDS in children by 2030.

Paediatric and Adolescent Treatment

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Ending AIDS in Children - JIAS Viewpoint on World Children's Day 2023

Assessment of the impact of social allowances on the quality of life of CLHIV in Tajikistan

rlekirkegaard — Wed, 25 Oct 2023 13:01:30 +0000

Assessment of the impact of social allowances on the quality of life of CLHIV in Tajikistan rlekirkegaard Wed, 10/25/2023 - 16:01

This report presents the results of a study commissioned by UNICEF Tajikistan in collaboration with the Republican AIDS Centre and the NGO Guli Surkh to evaluate the impact of social allowances on the treatment outcomes of children living with HIV in Tajikistan. Of the 7,552 persons living with HIV in Tajikistan today, 10.2 per cent are children under the age of 18. As of December 2017, 90.5 per cent of these children were covered with antiretroviral therapy.

HIV-Sensitive Social Protection

Organization Tag

UNICEF

Region Tags

Central and Eastern Europe

Population Tags

Adolescents

Topic Tags

Adolescents living with HIV

ART and Treatment

Combination prevention

Document Type Tags

National report

Year Tags

2018

Download file(s)

Report_Assessment of the impact of social allowances on the quality of life of CLWHIV_Eng.pdf

Integration of HIV and Testing and Linkage in Family Planning and Contraception Services

admin — Tue, 07 Jun 2022 11:18:32 +0000

Integration of HIV and Testing and Linkage in Family Planning and Contraception Services admin Tue, 06/07/2022 - 14:18

This brief addresses integration of HTS into FP services. It is intended as a practical resource for national health programmes seeking to introduce or scale up HIV testing and linkage to HIV prevention, STI, and antiretroviral therapy (ART) services in FP.

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Integration of HIV and Testing and Linkage in Family Planning and Contraception Services

Mental Health and Antiretroviral Treatment Adherence among Adolescents Living with HIV

admin — Tue, 04 Jan 2022 20:20:37 +0000

Mental Health and Antiretroviral Treatment Adherence among Adolescents Living with HIV  admin Tue, 01/04/2022 - 22:20

Building on research findings and effective interventions in low-and middle-income countries, this policy brief identifies key risks, including bullying and stigma, and facilitators, such as positive parenting and social support, that influence pathways between mental health and HIV outcomes for adolescents. It is part of a broader series that aims to support the translation of research into improved adolescent sexual reproductive health and HIV programming.

Good mental health and psychosocial wellbeing is especially important for adolescents during their transition to adulthood. It can support resilience and help initiate healthy behaviours that shape long-term positive health outcomes. Evidence shows that adolescents living with HIV are more likely to experience mental health challenges compared to their peers who do not have HIV. Poor mental health outcomes have been linked to low rates of adherence to life-saving antiretroviral treatment (ART) and retention in care. Understanding risk factors and protective factors that influence mental health and ART adherence amongst adolescents is critical for effective programming. Within eastern and southern Africa, there is great momentum to identify and scale-up interventions that address mental health and improve treatment, care and support for adolescents living with HIV.

Paediatric and Adolescent Treatment

Organization Tag

Partner

UNICEF

Region Tags

Eastern and Southern Africa

Topic Tags

Adolescents living with HIV

ART and Treatment

Document Type Tags

Brief

Year Tags

2021

Download file(s)

Policy brief: Mental health and treatment adherence among ALHIV

HIV Treatment, Care, and Support for Adolescents Living with HIV in Eastern and Southern Africa: A review of interventions for scale

rlekirkegaard — Thu, 10 Jun 2021 17:16:11 +0000

HIV Treatment, Care, and Support for Adolescents Living with HIV in Eastern and Southern Africa: A review of interventions for scale rlekirkegaard Thu, 06/10/2021 - 20:16

Adolescents in Eastern and Southern Africa (ESA) are key to achieving the global goal of ending the AIDS epidemic by 2030. ESA is home to 1.74 million adolescents living with HIV (ALHIV), representing 60 per cent of this population globally. In 12 ESA countries, AIDS is the leading cause of adolescent mortality. While there is an increasing focus on adolescents, the pace of progress remains slow, especially when compared with the growing needs of ALHIV.

It is time to deliver programmes at scale to address the needs of ALHIV, accelerating evidence of interventions producing results or showing significant promise for scale. This document examines and consolidates the current experiences of ALHIV programming in the region to support further implementation and scale-up of evidence-driven models. The findings serve as a call to action and the key considerations as a guide for governments and funding and implementing partners in scaling up service delivery to ALHIV.

Paediatric and Adolescent Treatment

HIV-Sensitive Social Protection

Organization Tag

UNICEF

Region Tags

Eastern and Southern Africa

Population Tags

Adolescents

Topic Tags

Adolescent friendly services

Adolescents living with HIV

ART and Treatment

Community engagement

Policy/Enabling Environment

Document Type Tags

Evidence and data

Year Tags

2021

Download file(s)

HIV Treatment, Care, and Support for Adolescents Living with HIV in Eastern and Southern Africa

Accelerating Access to Optimal Child-Friendly Antiretroviral Formulations for Children Living with HIV: Lessons Learned from Eight Sub-Saharan African Countries

rlekirkegaard — Fri, 28 May 2021 17:48:37 +0000

Accelerating Access to Optimal Child-Friendly Antiretroviral Formulations for Children Living with HIV: Lessons Learned from Eight Sub-Saharan African Countries rlekirkegaard Fri, 05/28/2021 - 20:48

EGPAF, with funding and support from Unitaid and DNDi, is bringing new-to-market pediatric ARV formulations to full-scale implementation in eight African countries. We gathered and documented lessons learned from these eight project countries to inform, streamline and accelerate the introduction and roll-out of new, child-friendly ARVs so that all children living with HIV have access to optimal, WHO-recommended treatment and care.

Paediatric and Adolescent Treatment

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Region Tags

Population Tags

Topic Tags

Paediatric ARVs and formulations

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