2023

Key considerations for fast-tracking EMTCT in lower-prevalence settings

IsabellaP — Wed, 03 Apr 2024 01:14:04 +0000

Key considerations for fast-tracking EMTCT in lower-prevalence settings IsabellaP Wed, 04/03/2024 - 04:14

This key considerations document, developed by UNICEF and WHO, expands on the 2020 “last mile” operational guidance, with specific considerations for countries with lower HIV prevalence. It builds on the experiences of countries that have been validated for EMTCT of HIV and syphilis and translates the valuable lessons and promising practices of these countries into an operational framework for national programmes, consisting of 12 strategies and enablers to guide efforts towards Fast-Tracking EMTCT in lower prevalence countries.

It is based on a review of experiences, key lessons learned and promising practices in implementation of EMTCT interventions in lower prevalence countries, including Sri Lanka and Thailand, which have been validated by WHO for having eliminated vertical transmission of HIV, and three countries with the potential to achieve EMTCT by 2030: the Democratic Republic of the Congo, Ghana and India.

PMTCT

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UNICEF

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East Asia and the Pacific

South Asia

West and Central Africa

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Sri Lanka

Thailand

Democratic Republic of the Congo

Ghana

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Infants

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Family centred care/services

Maternal, newborn and children health

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Key considerations for fast-tracking EMTCT in lower-prevalence settings

ayKP partnership webinar series

admin — Tue, 05 Mar 2024 22:48:11 +0000

ayKP partnership webinar series

Adolescent & Young Key Populations’ Leadership

admin Wed, 03/06/2024 - 00:48

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2023

Global Accelerated Action for the Health of Adolescents (AA-HA!) - Second edition

rlekirkegaard — Mon, 26 Feb 2024 20:26:37 +0000

Global Accelerated Action for the Health of Adolescents (AA-HA!) - Second edition rlekirkegaard Mon, 02/26/2024 - 22:26

This second edition of AA-HA! guidance to support country implementation builds on the first edition published in 2017. It is a collaborative effort spearheaded by the World Health Organization in collaboration with UNAIDS, UNESCO, UNFPA, UNICEF, UN WOMEN, the World Food Programme and PMNCH.

Building on the solid foundation of the first edition and voices of adolescents and young adults around the world, this multi-agency product has evolved to incorporate valuable learnings from the past six years, including of the COVID-19 pandemic's impacts. Latest estimates of mortality and disease burden, updated evidence, and a broader focus on wellbeing make the second edition a cutting-edge resource for policy makers in the area of adolescent health and well-being.

AA-HA! 2.0 offers insights into the current health and well-being landscape of the world’s over 1.2 billion adolescents, underlining evidence-based solutions and presenting strategies for priority setting, planning, implementing, and evaluating health and well-being programmes. The inclusion of key implementation strategies and real-world case studies make this guide a practical tool for governments in designing and implementing a new generation of adolescent health and well-being programmes.

Paediatric and Adolescent Treatment

Adolescent Prevention

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WHO

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Global

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Adolescents

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Adolescent friendly services

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Guidance

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2023

Introducing a framework for implementing triple elimination of mother-to-child transmission of HIV, syphilis and hepatitis B virus

rlekirkegaard — Fri, 23 Feb 2024 15:43:28 +0000

Introducing a framework for implementing triple elimination of mother-to-child transmission of HIV, syphilis and hepatitis B virus rlekirkegaard Fri, 02/23/2024 - 17:43

This 2023 framework from WHO and partners guides operationalization of a person-centred and integrated approach to interventions that country programmes can use to effectively scale-up triple elimination efforts and reach targets.

The novel Four Pillars Framework for Triple Elimination Implementation to guide country-led planning and implementation is aligned with the GHSS on HIV, viral hepatitis and sexually transmitted infections 2022−2030. The overarching goal of the framework is to support countries in operationalizing the move from single (HIV) and dual elimination (HIV and syphilis) to triple elimination of HIV, syphilis and HBV. This represents a major revision and modification of the 2002 UN “four-pronged strategy” for the elimination of new HIV infections among children and keeping their mother alive to include two additional conditions − syphilis and HBV − and reflects the significant updates that have been made to WHO’s technical recommendations and guidelines in the past decade.

The Four Pillars Framework focuses on distinct target populations and comprises a minimum package of essential services for each pillar:
(1) primary prevention of infection and vertical transmission
(2) SRH linkages and integration
(3) essential maternal EMTCT services and
(4) infant, child and partner services.

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Introducing a framework for implementing triple elimination of mother-to-child transmission of HIV, syphilis and HBV

Gender transformative approaches to achieve gender equality and SRHR

bbenghomari — Fri, 05 Jan 2024 19:41:36 +0000

Gender transformative approaches to achieve gender equality and SRHR bbenghomari Fri, 01/05/2024 - 21:41

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Gender transformative approaches to achieve gender equality and SRHR

Toolkit: Second edition of the youth guide to end online GBV

bbenghomari — Fri, 05 Jan 2024 19:25:09 +0000

Toolkit: Second edition of the youth guide to end online GBV bbenghomari Fri, 01/05/2024 - 21:25

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Toolkit: Second edition of the youth guide to end online GBV

Paediatric Abacavir/Lamivudine/Dolutegravir (pALD) fixed-dose combination: Introduction and rollout planning considerations for national programmes

rlekirkegaard — Thu, 21 Dec 2023 17:30:23 +0000

Paediatric Abacavir/Lamivudine/Dolutegravir (pALD) fixed-dose combination: Introduction and rollout planning considerations for national programmes rlekirkegaard Thu, 12/21/2023 - 19:30

Dolutegravir (DTG)-based HIV treatment regimens are recommended by the World Health Organization for children living with HIV (CLHIV) who weigh at least 3 kg. In 2020, the United States Food and Drug Administration (US FDA) granted tentative approval of paediatric DTG 10 mg scored, dispersible tablets (pDTG) for CLHIV weighing a minimum of 3 kg and at least four weeks of age. In early 2021, national HIV programmes in low- and middle-income countries (LMICs) began to transition CLHIV from treatment regimens containing non-nucleoside reverse transcriptase inhibitor (NNRTI) and lopinavir/ritonavir to pDTG. As of the last quarter of 2022, at least 73 countries have already placed or received orders for pDTG1 and an estimated 130,000 children have transitioned to pDTG. pDTG currently is administered along with optimised backbone antiretrovirals (ARVs) such as abacavir/lamivudine 120/60 mg scored dispersible tablets (pABC/3TC) per the WHO’s 2021 Consolidated HIV Guidelines.

This brief aims to inform the transition from pDTG + pABC/3TC to the new fixed-dose combination (FDC) dispersible tablet of paediatric ABC/3TC/DTG 60/30/5 mg (pALD).

Paediatric and Adolescent Treatment

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Paediatric ARVs and formulations

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