Why is this resource guide needed?
Bold, new ambitious HIV prevention targets agreed upon by the global community in 2021 call for a reduction of new HIV infections among girls and young women to less than 50,000 annually by 2025. Yet, as of 2020, the global community had wholly missed an opportunity to Fast-Track the reduction of new HIV infections among adolescent girls and young women by 75% to less than 100,000 new infections annually. It is clear that prevention of HIV, like other targets of the Sustainable Development Goals (SDG) framework, requires a re-think if we are do deliver for girls and young women.

The development process
A deep bench of collaborators (implementers, leading practitioners, academics, civil society organizations, and young women advocates) participated in consultations, interviews, and review panels as part of the development of this resource guide. Their contributions were supplemented with learnings from a series of evidence summaries, resulting in a rich resources informed by practical practitioner insights.

Who is this resource guide designed for?

This resource guide is designed for:

  • Public-sector programme managers (national and local)
  • Technical assistance providers
  • Policy-makers
  • Advocates

What does this resource guide contain?
Envisioned as an evergreen resource, this guide starts with the essential premise that there is much to be gained from distilling the learnings across girl- and young-women aligned movements, and across sectors.

The resource guide is anchored on the premise that a country-led response is essential for sustainable HIV prevention. This approach encourages decision-makers to articulate an data-driven vision, and to foster coordination across sectors to implement that vision.
The tools have been organized to avail in one comprehensive compendium, operational tools and resources that address the key programmatic decision gates.

How is this resource guide organized and delivered?
This resource guide includes nine modules. This compendium includes narrative syntheses summating key programming considerations, case studies, inventories of the programming landscape, and implementer resources (multimedia, manuals, tools curriculums, model laws).



  • M1: Strategic Planning
  • M2: Strategic Information
  • M3: Programme Scale-up for Population-level Impact


  • M4: Girl-centred Design
  • M5: Market Shaping and Innovation


  • M6: Changing Gender Norms
  • M7: Institutionalizing Multi-layered Prevention for Young Women and Girls
  • M8: Engaging Men and Boys


  • M9: Building Supportive Legal, Policy and Institutional Environments

What’s Next: Field Demonstrations
A light touch demonstration and feedback process is envisioned between November 2021 and March 2022, to elicit feedback on the applicability of this resource across numerous settings. This process will also identify areas where the content can continue to benefit from ongoing experiences, across different contexts. We welcome the collaboration of entities who have key resources and insights to offer our practitioner community, including national executives, southern-based institutions, centers of excellence, and girl- and young women-led collectives.